dc.contributor.author | Davis, EJ | en_US |
dc.contributor.author | Rathinam, SR | en_US |
dc.contributor.author | Okada, AA | en_US |
dc.contributor.author | Tow, SL | en_US |
dc.contributor.author | Petrushkin, H | en_US |
dc.contributor.author | Graham, EM | en_US |
dc.contributor.author | Chee, S-P | en_US |
dc.contributor.author | Guex-Crosier, Y | en_US |
dc.contributor.author | Jakob, E | en_US |
dc.contributor.author | Tugal-Tutkun, I | en_US |
dc.contributor.author | Cunningham, ET | en_US |
dc.contributor.author | Leavitt, JA | en_US |
dc.contributor.author | Mansour, AM | en_US |
dc.contributor.author | Winthrop, KL | en_US |
dc.contributor.author | Hills, WL | en_US |
dc.contributor.author | Smith, JR | en_US |
dc.date.accessioned | 2015-10-26T12:38:43Z | |
dc.date.available | 2012-04-30 | en_US |
dc.date.issued | 2012-12 | en_US |
dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/9220 | |
dc.description | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. | |
dc.description.abstract | PURPOSE: Tuberculous optic neuropathy may follow infection with Mycobacterium tuberculosis or administration of the bacille Calmette-Guerin. However, this condition is not well described in the ophthalmic literature. METHODS: Ophthalmologists, identified through professional electronic networks or previous publications, collected standardized clinical data relating to 62 eyes of 49 patients who they had managed with tuberculous optic neuropathy. RESULTS: Tuberculous optic neuropathy was most commonly manifested as papillitis (51.6 %), neuroretinitis (14.5 %), and optic nerve tubercle (11.3 %). Uveitis was an additional ocular morbidity in 88.7 % of eyes. In 36.7 % of patients, extraocular tuberculosis was present. The majority of patients (69.4 %) had resided in and/or traveled to an endemic area. Although initial visual acuity was 20/50 or worse in 62.9 % of 62 eyes, 76.7 % of 60 eyes followed for a median of 12 months achieved visual acuities of 20/40 or better. Visual field defects were reported for 46.8 % of eyes, but these defects recovered in 63.2 % of 19 eyes with follow-up. CONCLUSION: Visual recovery from tuberculous optic neuropathy is common, if the diagnosis is recognized and appropriate treatment is instituted. A tuberculous etiology should be considered when evaluating optic neuropathy in persons from endemic areas. | en_US |
dc.format.extent | 183 - 189 | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | J Ophthalmic Inflamm Infect | en_US |
dc.title | Clinical spectrum of tuberculous optic neuropathy. | en_US |
dc.type | Article | |
dc.identifier.doi | 10.1007/s12348-012-0079-5 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/22614321 | en_US |
pubs.issue | 4 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published | en_US |
pubs.volume | 2 | en_US |
dcterms.dateAccepted | 2012-04-30 | en_US |