• Login
    JavaScript is disabled for your browser. Some features of this site may not work without it.
    Investigating the diagnosis and management of bladder pain syndrome (BPS) in women with chronic pelvic pain (CPP). A study of prevalence, diagnostic tests, the effectiveness of neuromodulation, the quality of information available to patients and the discrepancies in rating the level of evidence for the management of BPS. 
    •   QMRO Home
    • Queen Mary University of London Theses
    • Theses
    • Investigating the diagnosis and management of bladder pain syndrome (BPS) in women with chronic pelvic pain (CPP). A study of prevalence, diagnostic tests, the effectiveness of neuromodulation, the quality of information available to patients and the discrepancies in rating the level of evidence for the management of BPS.
    •   QMRO Home
    • Queen Mary University of London Theses
    • Theses
    • Investigating the diagnosis and management of bladder pain syndrome (BPS) in women with chronic pelvic pain (CPP). A study of prevalence, diagnostic tests, the effectiveness of neuromodulation, the quality of information available to patients and the discrepancies in rating the level of evidence for the management of BPS.
    ‌
    ‌

    Browse

    All of QMROCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
    ‌
    ‌

    Administrators only

    Login
    ‌
    ‌

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Investigating the diagnosis and management of bladder pain syndrome (BPS) in women with chronic pelvic pain (CPP). A study of prevalence, diagnostic tests, the effectiveness of neuromodulation, the quality of information available to patients and the discrepancies in rating the level of evidence for the management of BPS.

    View/Open
    Tirlapur_Seema_MD(Res)_091215.pdf (6.188Mb)
    Publisher
    Queen Mary University of London
    Metadata
    Show full item record
    Abstract
    The aim of this thesis is to investigate the prevalence and management of bladder pain syndrome (BPS) amongst women with chronic pelvic pain (CPP) through a series of systematic reviews, a structured survey and primary study. It has been acknowledged that the diagnosis and management of BPS is a contentious subject. The mean prevalence of BPS in women with CPP is 61%. I initially carried out a patient and clinician survey to understand how BPS was being managed in the UK. I found wide variation in diagnostic methods and treatments of BPS used by clinicians and experienced by patients with no obvious consensus. Since we know the predominant complaint in these patients is pain (bladder or pelvic) I used patients with pelvic pain as my cohort. Cystoscopy is no longer used as a diagnostic test for BPS. It is possible to diagnose BPS through a consensus expert panel using symptom-based criteria. This method of deriving a reference standard is demonstrated in the primary study, since no gold standard diagnostic test exists for BPS. A case-control feasibility study was undertaken to investigate the accuracy of a group of urinary symptoms to diagnose BPS. While, neither index test of bladder filling pain or bladder wall tenderness can sensitively diagnose BPS alone, the symptoms of bladder filling pain, urinary frequency, pain on urination and pain on full bladder are a good predictor of the condition. A systematic review assessing the reporting outcomes identified five measures that should be included in studies; pain, urinary symptoms, general 8 wellbeing, quality of life and bladder capacity. Of the 19 treatments used for BPS, the level and strength of evidence ratings overestimated quality compared to the GRADE ratings. BPS can be diagnosed symptomatically but there is variable reporting of outcome measures and poor evidence for treatment effectiveness.
    Authors
    Tirlapur, Seema Anushka
    URI
    http://qmro.qmul.ac.uk/xmlui/handle/123456789/8970
    Collections
    • Theses [3321]
    Copyright statements
    The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the author
    Twitter iconFollow QMUL on Twitter
    Twitter iconFollow QM Research
    Online on twitter
    Facebook iconLike us on Facebook
    • Site Map
    • Privacy and cookies
    • Disclaimer
    • Accessibility
    • Contacts
    • Intranet
    • Current students

    Modern Slavery Statement

    Queen Mary University of London
    Mile End Road
    London E1 4NS
    Tel: +44 (0)20 7882 5555

    © Queen Mary University of London.