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dc.contributor.authorSchmidt-Hansen, M
dc.contributor.authorBaldwin, DR
dc.contributor.authorZamora, J
dc.date.accessioned2015-06-22T10:13:11Z
dc.date.issued2015-04-14
dc.date.issued2015-04-14
dc.date.issued2015-04-14
dc.date.issued2015-04-14
dc.identifier.urihttp://qmro.qmul.ac.uk/jspui/handle/123456789/7750
dc.description.abstractCLINICAL QUESTION: What is the sensitivity and specificity of 18F-fludeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) imaging for detecting mediastinal lymph node involvement in patients with potentially resectable non-small cell lung cancer (NSCLC)? BOTTOM LINE: Sensitivity and specificity of FDG-PET/CT imaging ranged from 0.77 to 0.81 for sensitivity and 0.79 to 0.90 for specificity, and were related to the brand of scanner, NSCLC subtype, FDG dose, and country of study origin. These sensitivities and specificities are not sufficiently accurate to warrant reliance on FDG-PET/CT scanning alone to make decisions about surgery as a single option for patients with potentially resectable NSCLC. Instead FDG-PET/CT imaging should be used to determine whether the next step should be biopsy (endobronchial ultrasound-guided biopsy or mediastinoscopy) or surgical resection.
dc.format.extent1465 - 1466
dc.languageENG
dc.subjectCarcinoma, Non-Small-Cell Lung
dc.subjectHumans
dc.subjectLung Neoplasms
dc.subjectLymph Nodes
dc.subjectMultimodal Imaging
dc.subjectPositron-Emission Tomography
dc.titleFDG-PET/CT imaging for mediastinal staging in patients with potentially resectable non-small cell lung cancer.
dc.typeJournal Article
dc.identifier.doi10.1001/jama.2015.2365
dc.relation.isPartOfJAMA
dc.relation.isPartOfJAMA
dc.relation.isPartOfJAMA
pubs.author-urlhttp://www.ncbi.nlm.nih.gov/pubmed/25871673
pubs.issue14
pubs.organisational-group/Queen Mary University of London
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry/Blizard Institute
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry/Blizard Institute/Centre for Primary Care and Public Health
pubs.publication-statusPublished
pubs.volume313


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