Continuous production of hollow hydrogel fibers with graphene inner wall

Abstract

Hydrogel fiber with spatiotemporal properties such as great aspect ratio, large surface area/volume ratio, orientation and knittability, has been considered as the potential application materials in the field of biomedicine area. On the basis of dynamic-crosslinking-spinning we reported before, a novel GO/PEG-PEGDA core-sheath hydrogel fiber was fabricated continuously. Moreover, uniform rGO-PEGDA hollow fiber was obtain after reduction process. The diameter of core and sheath can be controlled separately by adjusting extrusion rate of core solution and sheath solution, respectively. This novel series GO hybrid hydrogel fibers with core-shell or hollow structure have potential application on nerve and muscle tissue engineering.