Browsing Institute Director's Office by Title
Now showing items 46-65 of 117
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"I Thought I Was Controlling a Temporary Problem'': Exploring Patient Experience Along the Pathway to Diagnosis for Oesophageal and Gastric Cancer
(2018-03-15)Abstract from Qualitative Health Research Conference, 2017 -
The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma.
(2020-06)We performed a small interfering RNA screen to identify targets for cutaneous squamous cell carcinoma (cSCC) therapy in the ubiquitin/ubiquitin-like system. We provide evidence for selective anti-cSCC activity of knockdown ... -
Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Lower Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.
(2021-06)INTRODUCTION: Lower gastrointestinal (GI) cancers are a major cause of cancer deaths worldwide. Prognosis improves with earlier diagnosis, and non-invasive biomarkers have the potential to aid with early detection. Substantial ... -
Impact of the COVID-19 pandemic on cancer assessment in primary care: a qualitative study of GP views.
(2021-08)BACKGROUND: Early diagnosis is key to improve cancer outcomes, and most cancers are diagnosed in primary care after initial symptomatic presentation. Emerging evidence suggests an increase in avoidable cancer deaths owing ... -
Incorporating a brief intervention for personalised cancer risk assessment to promote behaviour change into primary care: a multi-methods pilot study.
(2021-01-23)BACKGROUND: Approximately 40% of cancers could be prevented if people lived healthier lifestyles. We have developed a theory-based brief intervention to share personalised cancer risk information and promote behaviour ... -
Integrated screening of migrants for multiple infectious diseases: Qualitative study of a city-wide programme.
(2020-04)Background: Migrants from certain regions are at increased risk of key infectious diseases (including HIV, tuberculosis (TB), hepatitis B and hepatitis C). Although guidelines increasingly recommend integrated screening ... -
Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126.
(2018-08)Chemical pollutant exposure is a risk factor contributing to the growing epidemic of non-alcoholic fatty liver disease (NAFLD) affecting human populations that consume a western diet. Although it is recognized that ... -
Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model.
(2019)Cutaneous squamous cell carcinomas are a common form of highly mutated keratinocyte skin cancers that are of particular concern in immunocompromised patients. Here we report on the efficacy of topically applied MS-275, a ... -
Long-term health outcomes of people with reduced kidney function in the UK: A modelling study using population health data.
(2020-12-16)BACKGROUND: People with reduced kidney function have increased cardiovascular disease (CVD) risk. We present a policy model that simulates individuals' long-term health outcomes and costs to inform strategies to reduce ... -
MA22.06 Longer Lung Cancer Time Intervals Amongst Culturally and Linguistically Diverse Patient Than Anglo-Australian Patients
(2019-10-01)Abstract MA22.06 -
MAVRIC: A Multicenter Randomized Controlled Trial of Transabdominal vs Transvaginal Cervical Cerclage
(2020-07-01)© Wolters Kluwer Health, Inc. All rights reserved. Womenwho experience multiple late miscarriages or spontaneous pretermbirths may be candidates for vaginal cerclage. In women with a history of pregnancy loss with vaginal ... -
Mechanisms Related to Inhibition of Fungal Biofilm Formation on Medical Device Coated with Poly(Methylmethacrylate-co-Dimethylacrylamide)
(2023-01-01)Candida albicans (C. albicans) are the most common cause of urinary fungal infections. C. albicans biofilms are of increasing clinical importance due to their resistance to antifungal therapy. Since the use of medical ...