Browsing Centre for Global Public Health by Author "Dartois, V"

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    • Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development. 

      Beites, T; O'Brien, K; Tiwari, D; Engelhart, CA; Walters, S; Andrews, J; Yang, H-J; Sutphen, ML; Weiner, DM; Dayao, EK (Nature Research, 2019-10-31)
      The viability of Mycobacterium tuberculosis (Mtb) depends on energy generated by its respiratory chain. Cytochrome bc1-aa3 oxidase and type-2 NADH dehydrogenase (NDH-2) are respiratory chain components predicted to be ...

    • Targeting protein biotinylation enhances tuberculosis chemotherapy. 

      Tiwari, D; Park, SW; Essawy, MM; Dawadi, S; Mason, A; Nandakumar, M; Zimmerman, M; Mina, M; Ho, HP; Engelhart, CA (2018-04-25)
      Successful drug treatment for tuberculosis (TB) depends on the unique contributions of its component drugs. Drug resistance poses a threat to the efficacy of individual drugs and the regimens to which they contribute. ...