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The Cellular Phenotype of the Neurodegenerative Disease Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.
(Queen Mary University of London, 2014-09)
Autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS) is an early onset neurodegenerative disorder resulting from mutations in the SACS gene that encodes the protein sacsin. Sacsin is a 520kDa multi-domain ...
The role of the aryl hydrocarbon receptor interacting protein (AIP) in pituitary tumorigenesis: A proteomic approach for explaining the clinical behaviour of AIP mutation-associated pituitary adenomas
(Queen Mary University of London, 2015-09-04)
A subset of familial and sporadic pituitary adenomas is due to germline mutations in the aryl
hydrocarbon receptor interacting protein gene (AIP). A systematic follow-up of cases and
families with AIP mutation ...
Aspects of brane world-volume dynamics in string theory
(Queen Mary University of London, 2012)
This thesis investigates the non-abelian dynamics of D-Brane systems in String
Theory, specifically focussing on the fate of the open string Tachyon. Starting from
the action of two coincident non-BPS D9-branes, we ...
Essays in Efficiency and Stability of the Banking Sector
(Queen Mary University of London, 19/05/2014)
This thesis contributes via the concept of efficiency in four distinct
fields of the fi nancial economics and banking literature: technological
heterogeneity, liquidity creation, profitability, and stability of banks.
In ...