Browsing Theses by Subject "argininosuccinate lyase"
Now showing items 1-1 of 1
-
The role of the tumour microenvironment in arginine deprivation in malignant pleural mesothelioma
(Queen Mary University of London, 2016-10-07)Approximately 50% of all malignant pleural mesotheliomas (MPM) are deficient in argininosuccinate synthetase (ASS1), the rate-limiting enzyme in arginine biosynthesis, and are sensitive to arginine deprivation. This discovery ...