Browsing Theses by Subject "Kras proto-oncogene"
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The role of epithelial cell-derived tumour necrosis Factor Alpha in pancreatic carcinogenesis
(Queen Mary University of London, 2012-03)Activating mutations of the kras proto-oncogene are found in more than 90 % of human pancreatic ductal adenocarcinoma (PDAC) and can result in increased activity of the NF-κB pathway, leading to constitutive production ...