Browsing Theses by Subject "Antivirals"
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REDUCED SENSITIVITY OF GENOTYPE 3 HEPATITIS C VIRUS TO DIRECT ACTING ANTIVIRALS
(Queen Mary University of London, 2018-07-16)Sofosbuvir is a uridine based nucleotide inhibitor of the hepatitis C viral (HCV) polymerase that is the backbone of many treatment regimens. In combination with drugs targeting other viral enzymes (including the poorly ...