Browsing Theses by Subject "Alzheimer's"
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Development of a novel model of optic neuritis to assess neuroprotective and repair strategies in multiple sclerosis
(Queen Mary University of London, 2012)Multiple sclerosis (MS) is a putative autoimmune disease of the central nervous system (CNS), which often affects the optic nerve pathway. Optic neuritis (ON) is a clinical feature of MS that can cause loss of vision due ... -
A Study into the Influence of Amyloid-beta Peptide Oxidation on the Rate of Fibril Formation, with a Synthesis of 2-oxo-histidine.
(Queen Mary University of London, 2012-05)The Amyloid Cascade Hypothesis states that fibrillation of the amyloid beta (Aβ) peptide is the primary cause of Alzheimer’s pathology. The trigger for the fibrillation is a subject of much debate, although it is clear, ...