Browsing Theses by Title
Now showing items 428-447 of 4201
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Cellular and molecular response to mechanical articular cartilage injury
(Queen Mary University of London, 2010)Joint injures frequently involve structural damage to articular cartilage and the underlying subchondral bone. The outcome of acute joint surface defects (JSD) varies from spontaneous healing to the development of ... -
Cellular and Molecular Signature of Oral Squamous Cell Carcinoma
(Queen Mary University of London, 2018-05-09)Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide. It is a result of numerous aetiological factors such as genetic predisposition, smoking, excessive alcohol consumption and viruses such as the ... -
Cellular and subcellular localised fluorescent probes to image mobile Zn2+
(Queen Mary University of London, 2020-10-04)Zn2+, as the second most abundant d-block metal in the human body, plays an important role in a wide range of biological processes, and the dysfunction of its homeostasis is related to many diseases, including Type 2 ... -
The Cellular Phenotype of the Neurodegenerative Disease Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.
(Queen Mary University of London, 2014-09)Autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS) is an early onset neurodegenerative disorder resulting from mutations in the SACS gene that encodes the protein sacsin. Sacsin is a 520kDa multi-domain ... -
Cellular Senescence and Cardiac Surgery Associated – Acute Kidney Injury.
(Queen Mary University of London, 2020-07-24)Introduction: Cardiac-surgery associated-acute kidney injury (CSA-AKI) is associated with increased morbidity and mortality. Furthermore, patients who develop CSA-AKI have higher incidences of progression to chronic renal ... -
Central Modulation of Visceral Pain Hypersensitivity.
(Queen Mary University of London, 2020)Background: visceral pain hypersensitivity is a key feature in functional gastrointestinal conditions. This condition leads to an exaggerated response to known painful stimuli, or chronic pain with no apparent trigger. ... -
The Centre of the Muniment’: the India Office Records and the Historiography of Early Modern Empire, 1875-1891
(Queen Mary University of London, 2014-09-24)archivists, antiquarians, geographers and civil servants within the India Office reorganised the records of the East India Company, the Board of Control and the India Office itself into what is now the India Office Records. ... -
Centrifuge and numerical modelling of twin-propped retaining walls.
(Queen Mary University of London, 1995)A series of tests on flexible model diaphragm walls embedded in an overconsolidated clay was carried out at the London Geotechnical Centrifuge Centre. The walls were propped at the crest and, following the simulation ... -
Cerebral organoids as a glioblastoma model to functionally validate and characterise genes of interest identified in omics approaches
Glioblastomas are the most common malignant brain tumours in adults, classified by the World Health Organisation (WHO) as Grade 4. These aggressive tumours present significant challenges due to their inter- and intra- ... -
The ceremonies of Charles II's court
(Queen Mary University of London, 2004)This thesis examines the question of how the restored monarchy used the ceremonies of court in the period 1660-1685. It is concerned with those rituals which took place regularly within the royal palaces, that is to say ... -
'Ceux de Guise': The Guise Family and their Affinity in Normandy, 1550-1600
(Queen Mary University of London, 1993)Despite their importance in. France and Europe in the sixteenth century, the Guise have received little archival study from historians this century. This thesis overturns the myths that have surrounded the family as a ... -
The Challenges of Designing and Implementing a Pilot Study of Ovarium Compositum in Infertile Women
(Queen Mary University of London, 2016-03-31)This thesis reports a research project with a mixed methods research design and a pragmatist worldview. It documents, analyses and reflects upon the evolution of a project, that over nine years, examined the challenges ... -
Changes in energy uxes during NPQ in LHCII and PSII-LHCII
(Queen Mary University of London, 2020-05-04)The non-photochemical quenching of excess energy (NPQ) is a fast molecular adaptation of photosynthetic organisms to variations of sunlight intensities. In plants, the energy-dependent quenching (qE) is the main NPQ ... -
Changes in innate immune function predict post-operative systemic inflammatory response syndrome (SIRS) following major Hepatico-pancreatico-biliary (HPB) surgery.
(Queen Mary University of London, 2014-10)Introduction Patients undergoing major surgery are at risk of life-threatening complications including systemic inflammatory response syndrome (SIRS) and sepsis. Early identification of patients at risk of SIRS would allow ... -
Changes in Lateral Stress During Slurry Trench Wall Installation.
(Queen Mary University of London, 1996)The thesis is concerned with the effects of slurry trenching (diaphragm wall installation) in an overconsolidated clay, with particular emphasis on the changes in lateral stress which occur. A review of the literature ... -
Changes in peripheral blood and tissue resident T cells in non-alcoholic fatty liver disease
(2022)Background and Aims: Non-alcoholic steatohepatitis (NASH), the inflammatory subtype of non-alcoholic fatty liver disease (NAFLD) associated with obesity and type2 diabetes mellitus (T2DM) can lead to advanced liver disease. ... -
Changes in the British and Irish flora - the role of genome size
(2023)Unprecedented anthropogenic changes are causing drastic shifts in biodiversity, species ranges and the survival of plants. Understanding which attributes put plants at risk is of vital importance for safeguarding the natural ... -
CHANGING LAND GOVERNANCE IN QUADRUPLE TRANSITION: CASES FROM BOSNIA-HERZEGOVINA AND KOSOVO
(Queen Mary University of London, 2018-07-17)Why and how do societies change institutions governing access to land after experiencing collectivism and conflict, and what form of economic governance emerges as a result? This empirically-focussed thesis examines changes ... -
Changing narratives of prostate cancer 1990-2010.
(Queen Mary University of London, 2015)Prostate cancer (PCa) is a unique and controversial disease. This is at least due to the high prevalence of latent disease, increasing amounts of which is being diagnosed, most of which is indolent and not lead to death, ... -
The characterisation of articular chondrocyte seeded chitosan hydrogels for cartilage tissue engineering
(2009)Cartilage is a type of connective tissue which has very little potential for spontaneous natural repair when damaged. The use of tissue engineering for the treatment of articular cartilage has been investigated for a number ...