Browsing Centre for Oral Immunobiology and Regenerative Medicine by Author "Uttagomol, J"
Now showing items 1-9 of 9
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Desmoglein 3 acts as a mechanosensor in keratinocytes
Uttagomol, J; Aguedo, A; Connelly, J; Wan, H (2018-05) -
The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53
Rehman, A; Cai, Y; Huenefeld, C; Jedlickova, H; Huang, Y; Teh, MT; Ahmad, US; Uttagomol, J; Wang, Y; Kang, A (Springer Nature, 2019-10-03)Desmoglein-3 (Dsg3), the Pemphigus Vulgaris (PV) antigen (PVA), plays an essential role in keratinocyte cell–cell adhesion and regulates various signaling pathways involved in the progression and metastasis of cancer where ... -
Evidence for desmoglein 3 as a mechanosensor in keratinocytes
Uttagomol, J; Connelly, J; Wan, H (2018) -
Evidence for Dsg3 in regulating Src signaling by competing with it for binding to caveolin-1.
Wan, H; Lin, K; Tsang, SM; Uttagomol, J (2016-03)This data article contains extended, complementary analysis related to the research articles entitled "Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src" (Tsang et al., 2010) [1] and ... -
Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces
Uttagomol, J; Ahmad, US; Rehman, A; Huang, Y; Laly, AC; Kang, A; Soetaert, J; Chance, R; Teh, M-T; Connelly, JT (MDPI, 2019-12-10)Desmoglein 3 (Dsg3) plays a crucial role in cell-cell adhesion and tissue integrity. Increasing evidence suggests that Dsg3 acts as a regulator of cellular mechanotransduction, but little is known about its direct role in ... -
Oxidative Stress-Mediated YAP Dysregulation Contributes to the Pathogenesis of Pemphigus Vulgaris
Huang, Y; Jedličková, H; Cai, Y; Rehman, A; Gammon, L; Ahmad, US; Uttagomol, J; Parkinson, EK; Fortune, F; Wan, H (Frontiers Media, 2021-04-19) -
Oxidative stress-mediated yes-associated protein dysregulation contributes to the pathogenesis of pemphigus vulgaris
Huang, Y; Jedlickova, H; Cai, Y; Rehman, A; Gammon, L; Ahmad, US; Uttagomol, J; Chance, R; Kang, A; Parkinson, EK (Frontiers Media, 2022-04-19)Pemphigus Vulgaris (PV) is a life-threatening autoimmune disease manifested with blisters in the skin and mucosa and caused by autoantibodies against adhesion protein desmoglein-3 (Dsg3) expressed in epithelial membrane ... -
The Regulation of the Hippo Pathway by Intercellular Junction Proteins
Ahmad, US; Uttagomol, J; Wan, H (2022) -
YAP Inhibition by Verteporfin Causes Downregulation of Desmosomal Genes and Proteins Leading to the Disintegration of Intercellular Junctions
Huang, Y; Ahmad, US; Rehman, A; Uttagomol, J; Wan, H (2022)