Browsing Centre for Oral Immunobiology and Regenerative Medicine by Author "Gnanapavan, S"

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    • A cell-based assay for the detection of neutralizing antibodies against alemtuzumab. 

      Ali, L; Saxena, G; Jones, M; Leisegang, GR; Gammon, L; Gnanapavan, S; Giovannoni, G; Schmierer, K; Baker, D; Kang, AS (2020-02-25)
      Aim: The humanized anti-CD52 monoclonal antibody alemtuzumab depletes lymphocytes and is currently used to treat relapsing multiple sclerosis. During treatment, anti-alemtuzumab antibodies may develop and reduce effective ...