Browsing Centre for Oral Immunobiology and Regenerative Medicine by Author "Getting, SJ"
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Exploiting formyl peptide receptor 2 to promote microglial resolution: a new approach to Alzheimer's disease treatment.
Wickstead, ES; Irving, MA; Getting, SJ; McArthur, S (2021-04-03)Alzheimer's disease and dementia are among the most significant current healthcare challenges given the rapidly growing elderly population, and the almost total lack of effective therapeutic interventions. Alzheimer's ... -
Reversal of beta-Amyloid-Induced Microglial ToxicityIn Vitroby Activation of Fpr2/3
Wickstead, ES; Karim, HA; Manuel, RE; Biggs, CS; Getting, SJ; McArthur, S (Hindawi, 2020-06-15) -
Stimulation of the Pro-Resolving Receptor Fpr2 Reverses Inflammatory Microglial Activity by Suppressing NFκB Activity.
Wickstead, ES; Elliott, BT; Pokorny, S; Biggs, C; Getting, SJ; McArthur, S (2023-11-06)Neuroinflammation driven primarily by microglia directly contributes to neuronal death in many neurodegenerative diseases. Classical anti-inflammatory approaches aim to suppress pro-inflammatory mediator production, but ...