Fabrication of Porous Bone Scaffolds Using Alginate and Bioactive Glass
View/ Open
Volume
10
Pagination
? - ? (14)
Publisher
Publisher URL
DOI
10.3390/jfb10010015
Journal
Journal of Functional Biomaterials
Issue
ISSN
2079-4983
Metadata
Show full item recordAbstract
Porous composite scaffold using an alginate and bioactive glass ICIE16M was synthesized by a simple freeze-drying technique. The scaffold was characterized using compression testing, Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), X-ray diffraction (XRD), X-ray microtomography (XMT) and scanning electron microscopy (SEM). The bioactivity of the scaffold was evaluated by its ability to form apatite on its surface in simulated body fluid (SBF). The data collected showed evidence that the novel material produced had an appropriate pore size for osteoconduction, with an average pore size of 110 μm and maximum pore size of 309 μm. Statistical analysis confirmed that the glass filler significantly (P < 0.05) increased the collapse yield of the scaffolds compared with pure alginate scaffolds. The ICIE16M glass had an amorphous structure, favorable for bioactivity.
Authors
Hatton, J; DAVIS, GR; Mourad, A-HI; Cherupurakal, N; HILL, R; MOHSIN, SCollections
Language
Licence information
Copyright statements
The following license files are associated with this item: