Browsing Biochemistry by Title
Now showing items 15-23 of 23
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A pangenome graph reference of 30 chicken genomes allows genotyping of large and complex structural variants.
(2023-11-22)BACKGROUND: The red junglefowl, the wild outgroup of domestic chickens, has historically served as a reference for genomic studies of domestic chickens. These studies have provided insight into the etiology of traits of ... -
Patagonian partnerships: the extinct Dusicyon avus and its interaction with prehistoric human communities.
(2024-04)The southern Mendoza province, located in the northern region of Patagonia, was inhabited by hunter-gatherer groups until historic times. Previous archaeological studies have reported canid remains among faunal assemblages, ... -
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.
(Elsevier, 2023-10-14)Centrosomes are the major microtubule-organizing centers in animals and play fundamental roles in many cellular processes. Understanding how their composition varies across diverse cell types and how it is altered in disease ... -
Seasonal dynamics of Arctic soils: Capturing year-round processes in measurements and soil biogeochemical models
(2024-07-01)The Arctic is undergoing rapid changes in climate, altering the status and functioning of high-latitude soils and permafrost. The vast majority of studies on Arctic soils and permafrost are conducted during the summer ... -
Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs.
(2024-03-28)Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules that have emerged as a therapeutic modality to induce targeted protein degradation (TPD) by harnessing cellular proteolytic degradation machinery. ... -
Suspended particles are hotspots of microbial remineralization in the ocean's twilight zone
(Elsevier, 2023-10-22)The sinking of photosynthetically produced organic carbon from the ocean surface to its interior is a significant term in the global carbon cycle. Most sinking organic carbon is, however, remineralized in the mesopelagic ... -
Unifying the mechanism of mitotic exit control in a spatiotemporal logical model.
(Public Library of Science, 2020-11)The transition from mitosis into the first gap phase of the cell cycle in budding yeast is controlled by the Mitotic Exit Network (MEN). The network interprets spatiotemporal cues about the progression of mitosis and ensures ...