Browsing School of Biological and Chemical Sciences by Subject "Zebrafish"
Now showing items 1-8 of 8
-
Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.
(2013-09-17)Centrioles organise centrosomes and template cilia and flagella. Several centriole and centrosome proteins have been linked to microcephaly (MCPH), a neuro-developmental disease associated with small brain size. CPAP (MCPH6) ... -
Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
(2018-05-29)Ciliopathies are a group of genetic disorders caused by a failure to form functional cilia. Due to a lack of structural information, it is currently poorly understood how ciliopathic mutations affect protein functionality ... -
The ontogeny of continuous quantity discrimination in zebrafish larvae (Danio rerio).
(Springer, 2020-04-15)Several studies have investigated the ontogeny of the capacity to discriminate between discrete numerical information in human and non-human animals. Contrarily, less attention has been devoted to the development of the ... -
Size discrimination in adult zebrafish (Danio rerio): Normative data and individual variation.
(2020-01-24)In humans, aging and neurodegenerative diseases have been found to be associated with impairment in both mathematical abilities and estimation of continuous quantities such as size, weight or distance. Zebrafish (Danio ... -
Total Nucleic Acid Extraction from Single Zebrafish Embryos for Genotyping and RNA-seq.
(Bio-protocol LLC, 2022-01-05)RNA sequencing allows for the quantification of the transcriptome of embryos to investigate transcriptional responses to various perturbations (e.g., mutations, infections, drug treatments). Previous protocols either lack ...