Browsing School of Biological and Chemical Sciences by Subject "Machine learning biomarker"

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    • A role for SETD2 loss in tumorigenesis through DNA methylation dysregulation. 

      Javaid, H; Barberis, A; Chervova, O; Nassiri, I; Voloshin, V; Sato, Y; Ogawa, S; Fairfax, B; Buffa, F; Humphrey, TC (Springer Nature, 2023-08-01)
      SETD2-dependent H3 Lysine-36 trimethylation (H3K36me3) has been recently linked to the deposition of de-novo DNA methylation. SETD2 is frequently mutated in cancer, however, the functional impact of SETD2 loss and depletion ...