dc.contributor.author | Giobbe, GG | |
dc.contributor.author | Zambon, A | |
dc.contributor.author | Vetralla, M | |
dc.contributor.author | Urbani, L | |
dc.contributor.author | Deguchi, K | |
dc.contributor.author | Pantano, MF | |
dc.contributor.author | Pugno, NM | |
dc.contributor.author | Elvassore, N | |
dc.contributor.author | De Coppi, P | |
dc.contributor.author | Spilimbergo, S | |
dc.date.accessioned | 2019-03-11T15:06:37Z | |
dc.date.available | 2019-03-11T15:06:37Z | |
dc.date.issued | 2018-10-22 | |
dc.identifier.citation | Giobbe, G., Zambon, A., Vetralla, M., Urbani, L., Deguchi, K., Pantano, M., Pugno, N., Elvassore, N., De Coppi, P. and Spilimbergo, S. (2018). Preservation over time of dried acellular esophageal matrix. Biomedical Physics & Engineering Express, [online] 4(6), p.065021. Available at: https://iopscience.iop.org/article/10.1088/2057-1976/aae4ff/meta [Accessed 11 Mar. 2019]. | en_US |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/56043 | |
dc.description.abstract | Preservation of acellular matrices represents a big challenge for the improvement of tissue engineering. In this work, a new method to preserve over time a decellularized esophageal scaffolds was explored. Dried and sterile acellular esophagi were obtained with a combined treatment of ethanol and a subsequent supercritical CO2 drying. Preservation of the extracellular matrix architecture, collagen content, and mechanical properties up to 6 months demonstrated the efficiency of the methodology with implications in natural scaffold storage. In vitro support of mesenchymal stem cells showed a promising indication to the further use of the technology in pre-clinical and clinical application. | en_US |
dc.publisher | IOP Publishing | en_US |
dc.relation.ispartof | Biomedical Physics and Engineering Express | |
dc.rights | This is a pre-copyedited, author-produced version of an article accepted for publication in Biomedical Physics & Engineering Express following peer review. The version of record is available https://iopscience.iop.org/article/10.1088/2057-1976/aae4ff/meta | |
dc.title | Preservation over time of dried acellular esophageal matrix | en_US |
dc.type | Article | en_US |
dc.rights.holder | © 2018 IOP Publishing Ltd | |
dc.identifier.doi | 10.1088/2057-1976/aae4ff | |
pubs.issue | 6 | en_US |
pubs.notes | 12 months | en_US |
pubs.notes | This is the accepted version of the publication. Embargo until 22 October 2019. | en_US |
pubs.publication-status | Published | en_US |
pubs.volume | 4 | en_US |
rioxxterms.funder | Default funder | en_US |
rioxxterms.identifier.project | Default project | en_US |