Centre for Primary Care and Public Health: Recent submissions
Now showing items 301-320 of 1689
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MAVRIC: a multicenter randomized controlled trial of transabdominal vs transvaginal cervical cerclage.
(Elsevier, 2020-03)BACKGROUND: Vaginal cerclage (a suture around the cervix) commonly is placed in women with recurrent pregnancy loss. These women may experience late miscarriage or extreme preterm delivery, despite being treated with ... -
Challenges of tuberculosis management in high and low prevalence countries in a mobile world
(Elsevier, 2014-02-28)In this issue of the PCRJ, Bishara et al. 1 present a case report about the treatment of a pregnant woman with tuberculosis (TB). She had emigrated from a country with a high prevalence of TB to one with a lower ... -
Pharmacist-led adherence support in general practice: a qualitative interview study of adults with asthma.
(BMJ Publishing Group Ltd, 2019-11-06)OBJECTIVES: The National Health Service (NHS) in England recently introduced general practice pharmacists (GPPs) to provide medication-focused support to both patients and the general practice team. This healthcare model ... -
Militaries and global health.
(Elsevier, 2019-09-14) -
Group-based cognitive stimulation therapy for dementia: a qualitative study on experiences of group interactions
Objectives: Cognitive Stimulation Therapy (CST) is an evidence-based group intervention shown to improve cognition and quality of life in dementia and is widely implemented across the NHS. However, no attempt has been made ... -
How pragmatic are the randomised trials used in recommendations for control of glycosylated haemoglobin levels in type 2 diabetic patients in general practice: an application of the PRECIS II tool.
(BioMed Central, 2020-03-19)BACKGROUND: Recommendations for good clinical practice have been reported to be difficult to apply in real life by primary care clinicians. This could be because the clinical trials at the origin of the guidelines are based ... -
Open randomised trial of the (Arabin) pessary to prevent preterm birth in twin pregnancy with health economics and acceptability: STOPPIT-2-a study protocol.
(2018-12-06)INTRODUCTION: The STOPPIT-2 study aims to determine the clinical utility of the Arabin cervical pessary in preventing preterm birth in women with a twin pregnancy and a short cervix, about which there is current uncertainty. ... -
Genotype-independent association between vitamin D deficiency and polycystic ovarian syndrome in Lahore, Pakistan.
(2020-02-10)Both vitamin D deficiency and single nucleotide polymorphisms (SNPs) in the gene encoding the vitamin D receptor (VDR) have been widely reported to associate with susceptibility to polycystic ovarian syndrome (PCOS). A ... -
Concussion and long-term cognitive impairment among professional or elite sport-persons: a systematic review.
(2020-02-27)INTRODUCTION: Understanding whether concussion in sport is associated with worsening cognitive function in later life will likely have immediate repercussion on sports concussion prevention and management policy and sporting ... -
A website for pilot and feasibility studies: giving your research the best chance of success.
(2019)This editorial introduces a website for pilot and feasibility studies. Pilot and feasibility studies are about giving research the best chance of success, but must be performed well to have the greatest benefit. The website ... -
To add or not to add a new treatment arm to a multiarm study: A decision-theoretic framework.
(2019-08-15)Multiarm clinical trials, which compare several experimental treatments against control, are frequently recommended due to their efficiency gain. In practise, all potential treatments may not be ready to be tested in a ... -
Optimal design when outcome values are not missing at random
(Institute of Statistical Science, 2018) -
Optimal design for experiments with possibly incomplete observations
(Institute of Statistical Science, 2018) -
D-optimal designs for multiarm trials with dropouts.
(2019-07-10)Multiarm trials with follow-up on participants are commonly implemented to assess treatment effects on a population over the course of the studies. Dropout is an unavoidable issue especially when the duration of the multiarm ...