Browsing Centre for Primary Care and Public Health by Author "Nadel, S"
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Restricted fluid bolus versus current practice in children with septic shock: the FiSh feasibility study and pilot RCT.
Inwald, D; Canter, RR; Woolfall, K; O'Hara, CB; Mouncey, PR; Zenasni, Z; Hudson, N; Saunders, S; Carter, A; Jones, N (2018-09)BACKGROUND: There has been no randomised controlled trial (RCT) of fluid bolus therapy in paediatric sepsis in the developed world despite evidence that excess fluid may be associated with harm. OBJECTIVES: To determine ... -
Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial.
Inwald, DP; Canter, R; Woolfall, K; Mouncey, P; Zenasni, Z; O'Hara, C; Carter, A; Jones, N; Lyttle, MD; Nadel, S (2018-08-07)OBJECTIVE: To determine the feasibility of Fluids in Shock, a randomised controlled trial (RCT) of restricted fluid bolus volume (10 mL/kg) versus recommended practice (20 mL/kg). DESIGN: Nine-month pilot RCT with embedded ...