Browsing Centre for Primary Care and Public Health by Title
Now showing items 935-954 of 1689
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A model of human lung fibrogenesis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis.
(2018-01-10)Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with limited therapeutic options. KCa3.1 ion channels play a critical role in TGFβ1-dependent pro-fibrotic responses in human lung myofibroblasts. ... -
Modelling Survival and Mortality Risk to 15 Years of Age for a National Cohort of Children with Serious Congenital Heart Defects Diagnosed in Infancy
(Public Library of Science, 2014-09-10)Congenital heart defects (CHDs) are a significant cause of death in infancy. Although contemporary management ensures that 80% of affected children reach adulthood, post-infant mortality and factors associated with death ... -
Modifiable risk factors for multiple sclerosis have consistent directions of effect across diverse ethnic backgrounds: a nested case-control study in an English population-based cohort.
(2023-09-07)BACKGROUND: Multiple sclerosis is a leading cause of non-traumatic neurological disability among young adults worldwide. Prior studies have identified modifiable risk factors for multiple sclerosis in cohorts of White ... -
Money for medication: financial incentives to improve medication adherence in assertive outreach.
(Royal College of Psychiatrists, 2007-01) -
Morality and values in support of universal healthcare must be enshrined in law. Comment on "Morality and Markets in the NHS".
(2015-03-12)This is a commentary on Gilbert and colleagues' (1) paper on morality and markets in the National Health Service (NHS). Morality and values are not ephemeral qualities and universal healthcare is not simply an aspiration; ... -
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.
(Nature Research, 2024-01-30)To date only a fraction of the genetic footprint of thyroid function has been clarified. We report a genome-wide association study meta-analysis of thyroid function in up to 271,040 individuals of European ancestry, including ... -
Multimorbidity in people living with and beyond cancer: a scoping review.
(2023)Globally, both cancer incidence and survival are increasing. Early cancer detection and improved treatment means many people with cancer will survive for ten or more years following diagnosis. Multimorbidity, defined as ...