Browsing Centre for Primary Care and Public Health by Title
Now showing items 1603-1622 of 1682
-
Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis.
(2019-06-05)Epidemiological evidence correlates low serum vitamin A (retinol) levels with increased susceptibility to active tuberculosis (TB); however, retinol is biologically inactive and must be converted into its bioactive form, ... -
Vitamin D and tuberculosis: where next?
(2018-08) -
Vitamin D attenuates rhinovirus-induced expression of intercellular adhesion molecule-1 (ICAM-1) and platelet-activating factor receptor (PAFR) in respiratory epithelial cells.
(2018-11-23)Human rhinoviruses commonly cause upper respiratory infections, which may be complicated by secondary bacterial infection. Vitamin D replacement reduces risk of acute respiratory infections in vitamin D-deficient individuals, ... -
Vitamin D deficiency associates with susceptibility to tuberculosis in Pakistan, but polymorphisms in VDR, DBP and CYP2R1 do not
(BioMed Central, 2016-05-10)Background: Single nucleotide polymorphisms (SNPs) in the genes encoding the vitamin D receptor (VDR) and the vitamin D binding protein (DBP) have been reported to modify the influence of vitamin D deficiency on susceptibility ... -
Vitamin D for the management of chronic obstructive pulmonary disease
(2019-03-25)Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. is is a protocol for a Cochrane Review (Intervention). The objectives are as follows: Our primary objectives are to determine whether Vitamin ... -
Vitamin D receptor genotype influences risk of upper respiratory infection.
(2018-10)SNP in the vitamin D receptor (VDR) gene is associated with risk of lower respiratory infections. The influence of genetic variation in the vitamin D pathway resulting in susceptibility to upper respiratory infections (URI) ... -
Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
(NIHR Journals Library, 2019-01)BACKGROUND: Randomised controlled trials (RCTs) exploring the potential of vitamin D to prevent acute respiratory infections have yielded mixed results. Individual participant data (IPD) meta-analysis has the potential to ... -
Vitamin D supplementation to prevent asthma exacerbations - Authors' reply.
(Elsevier, 2018-05-26) -
Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data.
(2017-11)BACKGROUND: A previous aggregate data meta-analysis of randomised controlled trials showed that vitamin D supplementation reduces the rate of asthma exacerbations requiring treatment with systemic corticosteroids. Whether ... -
Vitamin D to prevent exacerbations of COPD: systematic review and meta-analysis of individual participant data from randomised controlled trials.
(BMJ, 2019-01-10)BACKGROUND: Randomised controlled trials (RCTs) of vitamin D to prevent COPD exacerbations have yielded conflicting results.Individual participant data meta-analysis could identify factors that explain this variation. ...