Anatomic and Cellular Niches for Mycobacterium tuberculosis in Latent Tuberculosis Infection.
| dc.contributor.author | Mayito, J | en_US |
| dc.contributor.author | Andia, I | en_US |
| dc.contributor.author | Belay, M | en_US |
| dc.contributor.author | Jolliffe, DA | en_US |
| dc.contributor.author | Kateete, DP | en_US |
| dc.contributor.author | Reece, ST | en_US |
| dc.contributor.author | Martineau, AR | en_US |
| dc.date.accessioned | 2018-11-12T10:34:56Z | |
| dc.date.available | 2018-10-25 | en_US |
| dc.date.issued | 2019-02-15 | en_US |
| dc.date.submitted | 2018-10-31T15:14:10.196Z | |
| dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/49884 | |
| dc.description.abstract | Latent tuberculosis has been recognized for over a century, but discovery of new niches, where Mycobacterium tuberculosis resides, continues. We evaluated literature on M.tuberculosis locations during latency, highlighting that mesenchymal and hematopoietic stem cells harbor organisms in sensitized asymptomatic individuals. | en_US |
| dc.description.sponsorship | This work was supported by grants from the Medical Research Council (ref. MR/P024548/1; to A. R. M.) and the DELTAS Africa Initiative (ref. DEL-15-011 [to J. M.], via THRiVE-2). The DELTAS Africa Initiative is an independent funding scheme of the AAS’s Alliance for Accelerating Excellence in Science in Africa and supported by the NEPAD Agency with funding from the Wellcome Trust Grant No. 107742/Z/15/Z and the United Kingdom government. | en_US |
| dc.format.extent | 685 - 694 | en_US |
| dc.language | eng | en_US |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | J Infect Dis | en_US |
| dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. | |
| dc.subject | CD34 | en_US |
| dc.subject | bone marrow | en_US |
| dc.subject | hematopoietic stem cells | en_US |
| dc.subject | latent tuberculosis | en_US |
| dc.subject | mesencymal stem cells | en_US |
| dc.subject | Hematopoietic Stem Cells | en_US |
| dc.subject | Humans | en_US |
| dc.subject | Latent Tuberculosis | en_US |
| dc.subject | Mesenchymal Stem Cells | en_US |
| dc.subject | Mycobacterium tuberculosis | en_US |
| dc.subject | Phagocytes | en_US |
| dc.title | Anatomic and Cellular Niches for Mycobacterium tuberculosis in Latent Tuberculosis Infection. | en_US |
| dc.type | Article | |
| dc.rights.holder | © The Author(s) 2018. | |
| dc.identifier.doi | 10.1093/infdis/jiy579 | en_US |
| pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/30376080 | en_US |
| pubs.issue | 5 | en_US |
| pubs.notes | No embargo | en_US |
| pubs.publication-status | Published | en_US |
| pubs.volume | 219 | en_US |
| dcterms.dateAccepted | 2018-10-25 | en_US |
| qmul.funder | Evaluation of a novel microbiological diagnostic test for latent tuberculosis infection in Ethiopia (Micro-LTBI)::Medical Research Council | en_US |
