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dc.contributor.authorNibali, Len_US
dc.contributor.authorYeh, Y-Cen_US
dc.contributor.authorPometti, Den_US
dc.contributor.authorTu, Y-Ken_US
dc.date.accessioned2018-11-09T16:34:02Z
dc.date.available2018-10-01en_US
dc.date.issued2018-12en_US
dc.date.submitted2018-10-18T22:54:18.610Z
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/49825
dc.description.abstractAIM: The aim of this study was to assess the stability over time of periodontal intrabony defects treated with minimally invasive non-surgical therapy (MINST) and supportive periodontal therapy (SPT). METHODS: Clinical and radiographic analysis was carried out in 21 intrabony defects treated with MINST in 14 consecutive patients included in a prospective study and reassessed after 5 years of SPT. Baseline, 1- and 5-year radiographs were analysed, and bone levels were compared by multilevel linear regression adjusted by latent variable method. RESULTS: None of the 21 teeth with intrabony defects was lost at 5 years. Average probing pocket depth, clinical attachment level and radiographic intrabony vertical defect depth reductions were 3.6, 3.5 and 2.6 mm, respectively, 5 years after treatment (p < 0.001 compared with baseline). Further non-statistically significant reductions were seen in clinical and radiographic measures between 1 and 5 years. Deeper initial defects and narrower angles were predictive of a bigger reduction in defect depth (p < 0.001 and p = 0.017, respectively). CONCLUSIONS: Clinical and radiographic improvements in intrabony defects after MINST seen at 1 year are stable up to 5 years, bringing evidence to support its long-term efficacy for the treatment of intrabony defects in non-smokers.en_US
dc.description.sponsorshipNo specific funding was obtained for the analysis reported in this paper.en_US
dc.format.extent1458 - 1464en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofJ Clin Periodontolen_US
dc.rights"This is the peer reviewed version of the following article: Nibali L, Yeh Y‐C, Pometti D, Tu Y‐K. Long‐term stability of intrabony defects treated with minimally invasive non‐surgical therapy. J Clin Periodontol. 2018;00:1–7. Doi: 10.1111/jcpe.13021 which will be published in final form at https://doi.org/10.1111/jcpe.13021. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions."
dc.subjectintrabony defectsen_US
dc.subjectminimally invasiveen_US
dc.subjectnon-surgical therapyen_US
dc.subjectperiodontitisen_US
dc.subjectradiographic bone gainen_US
dc.titleLong-term stability of intrabony defects treated with minimally invasive non-surgical therapy.en_US
dc.typeArticle
dc.identifier.doi10.1111/jcpe.13021en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/30307641en_US
pubs.issue12en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume45en_US
dcterms.dateAccepted2018-10-08en_US


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