Institute of Dentistry: Recent submissions
Now showing items 861-880 of 1450
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Immunomodulatory role of Keratin 76 in oral and gastric cancer
(Springer Science and Business Media LLC, 2018-08-24) -
Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes
Abnormal keratinocyte differentiation is fundamental to pathologies such as skin cancer and mucosal inflammatory diseases. The ability to grow keratinocytes in vitro allows the study of differentiation however any translational ... -
Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes.
(2020-03-16)Abnormal keratinocyte differentiation is fundamental to pathologies such as skin cancer and mucosal inflammatory diseases. The ability to grow keratinocytes in vitro allows the study of differentiation however any translational ... -
Children's pain history reported by parents and children attending a UK teaching hospital's dental emergency clinic
(2019-07-06)Background: The 2013 UK Children's Dental Health Survey found that 37% of five‐year‐olds and more than half (55%) of eight year‐olds had a dental problem that had caused pain in the previous six months. This study focused ... -
A cell-based assay for the detection of neutralizing antibodies against alemtuzumab.
(2020-02-25)Aim: The humanized anti-CD52 monoclonal antibody alemtuzumab depletes lymphocytes and is currently used to treat relapsing multiple sclerosis. During treatment, anti-alemtuzumab antibodies may develop and reduce effective ... -
Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation.
(2020-03-02)Understanding the circuits that promote an efficient resolution of inflammation is crucial to deciphering the molecular and cellular processes required to promote tissue repair. Macrophages play a central role in the ... -
Most recommended medical interventions reach P<0.005 for their primary outcomes in meta-analyses.
(2019-11-25)BACKGROUND: It has been proposed that the threshold of statistical significance should shift from P-value < 0.05 to P-value < 0.005, but there is concern that this move may dismiss effective, useful interventions. We aimed ... -
Strontium- and Zinc-Containing Bioactive Glass and Alginates Scaffolds.
(2020-01-13)With an increasingly elderly population, there is a proportionate increase in bone injuries requiring hospitalization. Clinicians are increasingly adopting tissue-engineering methods for treatment due to limitations in the ... -
Infographic: Oral health in elite athletes
(2017-05)