Browsing School of Engineering and Materials Science by Author "Wann, A. K. T"
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Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells
McMurry, R. J; Wann, A. K. T; Thompson, C. L; Connelly, J. T; Knight, M. M (Nature Publishing Group, 2013)The primary cilium regulates cellular signalling including influencing wnt sensitivity by sequestering β-catenin within the ciliary compartment. Topographic regulation of intracellular actin-myosin tension can control stem ...