Browsing School of Engineering and Materials Science by Author "Larcombe, MR"
Now showing items 1-1 of 1
-
Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming
Knaupp, AS; Buckberry, S; Pflueger, J; Lim, SM; Ford, E; Larcombe, MR; Rossello, FJ; de Mendoza, A; Alaei, S; Firas, J (Elsevier, 2017-12-07)Somatic cell reprogramming into induced pluripotent stem cells (iPSCs) induces changes in genome architecture reflective of the embryonic stem cell (ESC) state. However, only a small minority of cells typically transition ...