Browsing School of Engineering and Materials Science by Author "Kyriacou, PA"
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Comparison of a Genetic Algorithm Variable Selection and Interval Partial Least Squares for quantitative analysis of lactate in PBS.
Mamouei, M; Qassem, M; Budidha, K; Baishya, N; Vadgama, P; Kyriacou, PA (2019-07)Blood lactate is an important biomarker that has been linked to morbidity and mortality of critically ill patients, acute ischemic stroke, septic shock, lung injuries, insulin resistance in diabetic patients, and cancer. ... -
In vitro quantification of lactate in Phosphate Buffer Saline (PBS) samples.
Budidha, K; Mamouei, M; Baishya, N; Vadgama, P; Kyriacou, PA (2019-07)Continuous measurement of lactate levels in the blood is a prerequisite in intensive care patients who are susceptible to sepsis due to their suppressed immune system and increased metabolic demand. Currently, there exists ... -
Near infrared spectrometric investigation of lactate in a varying pH buffer
Baishya, N; Momouei, M; Budidha, K; Qassem, M; Vadgama, P; Kyriacou, PA (SAGE, 2020-03-31)Lactic acidosis is commonly observed in various disease states in critical care and can be adopted as a hemodynamic biomarker, as well as a target for therapy. pH is the main biomarker for the diagnosis of acid–base disorders ... -
Near Infrared Spectrometric Investigations on the behaviour of Lactate.
Baishya, N; Budidha, K; Mamouei, M; Qassem, M; Vadgama, P; Kyriacou, PA (2019-07)In patients with life-threatening illnesses, the metabolic production and disposal of lactate are impaired, which leads to a build-up of blood lactate. In critical care units, the changes in lactate levels are measured ...