Browsing School of Engineering and Materials Science by Author "Iskratsch, T"
Now showing items 21-35 of 35
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Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells
Tabdanov, E; Gondarenko, S; Kumari, S; Liapis, A; Dustin, ML; Sheetz, MP; Kam, LC; Iskratsch, T (2015) -
Mix and (mis-)match - The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart.
Ward, M; Iskratsch, T (Elsevier, 2019-02-08)The composition and the stiffness of cardiac microenvironment change during development and/or in heart disease. Cardiomyocytes (CMs) and their progenitors sense these changes, which decides over the cell fate and can ... -
Myonuclear alterations associated with exercise are independent of age in humans
Battey, E; Ross, JA; Hoang, A; Wilson, DGS; Han, Y; Levy, Y; Pollock, RD; Kalakoutis, M; Pugh, JN; Close, GL (2023) -
N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading
Zhang, X; Moore, SW; Iskratsch, T; Sheetz, MP (2014-04-01) -
Photoelectrochemical imaging of single cardiomyocytes and monitoring of their action potentials through contact force manipulation of organoids
Jacques, R; Zhou, B; Marhuenda, E; Gorecki, J; Das, A; Iskratsch, T; Krause, S (2023) -
Polymer fiber-based models of connective tissue repair and healing
Lee, NM; Erisken, C; Iskratsch, T; Sheetz, M; Levine, WN; Lu, HH (2017-01) -
Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching
Swiatlowska, P; Sit, B; Feng, Z; Marhuenda, E; Xanthis, I; Zingaro, S; Ward, M; Zhou, X; Xiao, Q; Shanahan, C (2022) -
Regulation of cardiomyocyte adhesion and mechanosignalling through distinct nanoscale behaviour of integrin ligands mimicking healthy or fibrotic extracellular matrix.
Hawkes, W; Marhuenda, E; Reynolds, P; O'Neill, C; Pandey, P; Samuel Wilson, DG; Freeley, M; Huang, D; Hu, J; Gondarenko, S (2022-11-21)The stiffness of the cardiovascular environment changes during ageing and in disease and contributes to disease incidence and progression. Changing collagen expression and cross-linking regulate the rigidity of the cardiac ... -
The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction
Wilson, DGS; Tinker, A; Iskratsch, T (2022) -
Similar Effects of Humoral or Mechanical Stress on Cell-Cell Contacts in Cultured Cardiomyocytes
Koldyka, O; Pandey, P; Iskratsch, T; Ehler, E (2018-02-02) -
Sox9 Accelerates Vascular Ageing by Regulating Extracellular Matrix Composition and Stiffness
Faleeva, M; Ahmad, S; Theofilatos, K; Lynham, S; Watson, G; Whitehead, M; Marhuenda, E; Iskratsch, T; Cox, S; Shanahan, CM -
Tools for studying and modulating (cardiac muscle) cell mechanics and mechanosensing across the scales.
Swiatlowska, P; Iskratsch, T (2021-10)Cardiomyocytes generate force for the contraction of the heart to pump blood into the lungs and body. At the same time, they are exquisitely tuned to the mechanical environment and react to e.g. changes in cell and ... -
Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices
Wolfenson, H; Meacci, G; Liu, S; Stachowiak, MR; Iskratsch, T; Ghassemi, S; Roca-Cusachs, P; O'Shaughnessy, B; Hone, J; Sheetz, MP (2016-01) -
Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and-861
Pedrosa, A-R; Bodrug, N; Gomez-Escudero, J; Carter, EP; Reynolds, LE; Georgiou, PN; Fernandez, I; Lees, DM; Kostourou, V; Alexopoulou, AN (2019-09-01) -
Two distinct phosphorylation events govern the function of muscle FHOD3
Iskratsch, T; Reijntjes, S; Dwyer, J; Toselli, P; Degano, IR; Dominguez, I; Ehler, E (2013-03)