Browsing Centre for Preventative Neurology by Title
Now showing items 47-66 of 134
-
Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia.
(2020-01-01)Parkinson's disease is a genetically complex disorder. Multiple genes have been shown to contribute to the risk of Parkinson's disease, and currently 90 independent risk variants have been identified by genome-wide association ... -
Genetic risk of Parkinson disease and progression: An analysis of 13 longitudinal cohorts
(2019-08-01)Copyright © 2019 The Author(s). Objective To determine if any association between previously identified alleles that confer risk for Parkinson disease and variables measuring disease progression. Methods We evaluated the ... -
Hearing and dementia
(2016-11) -
The Impact of COVID-19 on Access to Parkinson's Disease Medication.
(2020-08-28)BACKGROUND: Many countries have implemented drastic measures to fight the COVID-19 pandemic. Restrictions and diversion of resources may have negatively affected patients with Parkinson's disease (PD). Our aim was to examine ... -
The Impact of COVID-19 on the Employment of People With Multiple Sclerosis: A Multi-Methods Study
(Consortium of Multiple Sclerosis Centers, 2024-01-22) -
Impact of rituximab treatment regime on time to relapse in aquaporin-4 antibody positive neuromyelitis optica spectrum disorder.
(2024-03-07)BACKGROUND: Aquaporin-4 (AQP4) antibody associated neuromyelitis optica (NMOSD) requires long-term immunosuppression. Rituximab is increasingly used worldwide, however the optimal regime is not established. METHODS: We ... -
Improving estimation of Parkinson's disease risk - The enhanced PREDICT-PD algorithm
(2020-03-23)medRxiv preprint -
Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease.
(Elsevier, 2017-12-20)SNCA missense mutations are a rare cause of autosomal dominant Parkinson's disease (PD). To date, 6 missense mutations in SNCA have been nominated as causal. Here, we assess the frequency of these 6 mutations in public ... -
Investigation of Autosomal Genetic Sex Differences in Parkinson's disease.
(2021-04-26)OBJECTIVE: Parkinson's disease (PD) is a complex neurodegenerative disorder. Males are on average ~ 1.5 times more likely to develop PD compared to females with European ancestry. Over the years genome-wide association ... -
Isolated rapid eye movement sleep behaviour disorder (iRBD) in the Island Study Linking Ageing and Neurodegenerative Disease (ISLAND) Sleep Study: protocol and baseline characteristics.
(2023-11-28)Isolated rapid eye movement (REM) sleep behaviour disorder (iRBD) is a sleep disorder that is characterised by dream enactment episodes during REM sleep. It is the strongest known predictor of α-synuclein-related ...