Browsing Centre for Preventative Neurology by Title
Now showing items 119-137 of 137
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Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis
(Wiley, 2019-02-05)Objective: To identify shared polygenic risk and causal associations in amyotrophic lateral sclerosis (ALS). Methods: Linkage disequilibrium score regression and Mendelian randomization were applied in a large‐scale, ... -
A study of referral bias in NMOSD and MOGAD cohorts.
(2024-03-14)BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are rare disorders often seen in highly specialized services or tertiary centres. We ... -
Suspecting dementia: canaries, chameleons and zebras.
(2021-07-02)The early and accurate diagnosis of dementia is more important than ever before but remains challenging. Dementia is increasingly the business of neurologists and, with ageing populations worldwide, will become even more ... -
Testing shortened versions of smell tests to screen for hyposmia in Parkinson’s disease
Background Hyposmia is an early feature in neurodegenerative diseases, most notably Parkinson's Disease (PD). Using abbreviated smell tests could provide a cost‐effective means for large‐scale hyposmia screening. It is ... -
Under & Over: A randomised controlled study to develop an upper limb rehabilitation tool for people with Multiple Sclerosis.
(2024-03-01)BACKGROUND: Impairment of upper limb function is common in Multiple Sclerosis (MS). Rehabilitation remains a key strategy to manage symptoms and improve quality of life. The Under & Over study assessed the effectiveness ...