dc.contributor.author | Hosseini, G | en_US |
dc.contributor.author | Ji, C | en_US |
dc.contributor.author | Xu, D | en_US |
dc.contributor.author | Rezaienia, MA | en_US |
dc.contributor.author | Avital, E | en_US |
dc.contributor.author | Munjiza, A | en_US |
dc.contributor.author | Williams, JJR | en_US |
dc.contributor.author | Green, JSA | en_US |
dc.date.accessioned | 2017-12-08T15:43:40Z | |
dc.date.available | 2017-10-24 | en_US |
dc.date.issued | 2018-02 | en_US |
dc.date.submitted | 2017-11-21T15:49:37.009Z | |
dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/29444 | |
dc.description.abstract | The aim of this study is to create a computational model of the human ureteral system that accurately replicates the peristaltic movement of the ureter for a variety of physiological and pathological functions. The objectives of this research are met using our in-house fluid-structural dynamics code (CgLes-Y code). A realistic peristaltic motion of the ureter is modelled using a novel piecewise linear force model. The urodynamic responses are investigated under two conditions of a healthy and a depressed contraction force. A ureteral pressure during the contraction shows a very good agreement with corresponding clinical data. The results also show a dependency of the wall shear stresses on the contraction velocity and it confirms the presence of a high shear stress at the proximal part of the ureter. Additionally, it is shown that an inefficient lumen contraction can increase the possibility of a continuous reflux during the propagation of peristalsis. | en_US |
dc.format.extent | 117 - 125 | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Biomed Eng Lett | en_US |
dc.subject | CFD | en_US |
dc.subject | PUJ | en_US |
dc.subject | Reflux | en_US |
dc.subject | Ureter | en_US |
dc.subject | VUJ | en_US |
dc.subject | VUR | en_US |
dc.title | A computational model of ureteral peristalsis and an investigation into ureteral reflux. | en_US |
dc.type | Article | |
dc.rights.holder | © Korean Society of Medical and Biological Engineering and Springer-Verlag GmbH Germany, part of Springer Nature 2017 | |
dc.identifier.doi | 10.1007/s13534-017-0053-0 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/30603196 | en_US |
pubs.issue | 1 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published online | en_US |
pubs.volume | 8 | en_US |
dcterms.dateAccepted | 2017-10-24 | en_US |