Type of obstetric anesthesia administered and complications in women with preeclampsia in low- and middle-income countries: A systematic review.
dc.contributor.author | Sobhy, S | en_US |
dc.contributor.author | Dharmarajah, K | en_US |
dc.contributor.author | Arroyo-Manzano, D | en_US |
dc.contributor.author | Navanatnarajah, R | en_US |
dc.contributor.author | Noblet, J | en_US |
dc.contributor.author | Zamora, J | en_US |
dc.contributor.author | Thangaratinam, S | en_US |
dc.date.accessioned | 2017-12-08T14:26:41Z | |
dc.date.available | 2017-10-05 | en_US |
dc.date.issued | 2017-11 | en_US |
dc.date.submitted | 2017-11-12T07:24:25.802Z | |
dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/29403 | |
dc.description.abstract | BACKGROUND: Delivery is often expedited with cesarean section, necessitating anesthesia, to prevent complications in women with preeclampsia. Anesthesia-associated risks in these women from low- and middle-income countries (LMICs) are not known. METHODS: We searched major databases (until February 2017) for studies on general vs. regional anesthesia in women with preeclampsia. We summarized the association between outcomes and type of anesthesia using a random effects model and reported as odds ratio (OR) with 95% confidence intervals (95% CIs). FINDINGS: We included 14 studies (10,411 pregnancies). General anesthesia was associated with an increase in the odds of maternal death sevenfold (OR 7.70, 95% CI 1.9 to 31.0, I2 = 58%) than regional anesthesia. The odds of pulmonary edema (OR 5.16, 95% CI 2.5 to 10.4, I2 = 0%), maternal intensive care unit admissions (OR 16.25, 95% CI 9.0 to 29.5, I2 = 65%), and perinatal death (OR 3.01, 95% CI 1.4 to 6.5, I2 = 56%) were increased with general vs. regional anesthesia. CONCLUSION: General anesthesia is associated with increased complications in women with preeclampsia undergoing cesarean section in LMIC. | en_US |
dc.format.extent | 326 - 336 | en_US |
dc.language | eng | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Hypertens Pregnancy | en_US |
dc.subject | Preeclampsia | en_US |
dc.subject | anesthesia | en_US |
dc.subject | maternal mortality | en_US |
dc.subject | Anesthesia, General | en_US |
dc.subject | Anesthesia, Obstetrical | en_US |
dc.subject | Delivery, Obstetric | en_US |
dc.subject | Female | en_US |
dc.subject | Humans | en_US |
dc.subject | Maternal Mortality | en_US |
dc.subject | Pre-Eclampsia | en_US |
dc.subject | Pregnancy | en_US |
dc.title | Type of obstetric anesthesia administered and complications in women with preeclampsia in low- and middle-income countries: A systematic review. | en_US |
dc.type | Article | |
dc.rights.holder | “This is an Accepted Manuscript of an article published by Taylor & Francis in Hypertension in Pregnancy on 10 Nov 2017, available online: https://doi.org/10.1080/10641955.2017.1389951 .” | |
dc.identifier.doi | 10.1080/10641955.2017.1389951 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/29125378 | en_US |
pubs.issue | 4 | en_US |
pubs.notes | No embargo | en_US |
pubs.publication-status | Published | en_US |
pubs.volume | 36 | en_US |