Now showing items 1-3 of 3

    • Conserved roles for Hnf4 family transcription factors in zebrafish development and intestinal function. 

      Heppert, JK; Lickwar, CR; Tillman, MC; Davis, BR; Davison, JM; Lu, H-Y; Chen, W; Busch-Nentwich, EM; Corcoran, DL; Rawls, JF (2022-11-30)
      Transcription factors play important roles in the development of the intestinal epithelium and its ability to respond to endocrine, nutritional, and microbial signals. Hepatocyte nuclear factor 4 family nuclear receptors ...
    • Gaucher disease protects against tuberculosis. 

      Fan, J; Hale, VL; Lelieveld, LT; Whitworth, LJ; Busch-Nentwich, EM; Troll, M; Edelstein, PH; Cox, TM; Roca, FJ; Aerts, JMFG (2023-02-14)
      Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease, characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in macrophages. Gaucher and other lysosomal diseases occur ...
    • Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri. 

      Torraca, V; White, RJ; Sealy, IM; Mazon-Moya, M; Duggan, G; Willis, AR; Busch-Nentwich, EM; Mostowy, S (Disease Models & Mechanisms, 2024-01-26)
      Shigella flexneri is a human-adapted pathovar of Escherichia coli that can invade the intestinal epithelium, causing inflammation and bacillary dysentery. Although an important human pathogen, the host response to S. ...