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Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity.
(2016-11-10)
3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial ...