Browsing School of Biological and Chemical Sciences by Subject "Ubiquitin-Protein Ligases"
Now showing items 1-2 of 2
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Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)
(Royal Society of Chemistry (RSC), 2022-09-29) -
Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs.
(2024-03-28)Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules that have emerged as a therapeutic modality to induce targeted protein degradation (TPD) by harnessing cellular proteolytic degradation machinery. ...