Browsing School of Biological and Chemical Sciences by Subject "Synucleins"

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    • Epitope mapping and specificity of the anti-alpha-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines. 

      Perrin, RJ; Payton, JE; Barnett, DH; Wraight, CL; Woods, WS; Ye, L; George, JM (2003-10-02)
      While alpha- and beta-synuclein largely overlap in their expression in the vertebrate brain, only alpha-synuclein accumulates in the fibrillar aggregates typical of Parkinson's disease. It is thus critical to have immunological ...

    • The synucleins. 

      George, JM (2002)
      SUMMARY: Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. All synucleins ...