Now showing items 1-2 of 2

    • Serotonin depletion impairs both Pavlovian and instrumental reversal learning in healthy humans. 

      Kanen, JW; Apergis-Schoute, AM; Yellowlees, R; Arntz, FE; van der Flier, FE; Price, A; Cardinal, RN; Christmas, DM; Clark, L; Sahakian, BJ (Springer Nature, 2021-08-24)
      Serotonin is involved in updating responses to changing environmental circumstances. Optimising behaviour to maximise reward and minimise punishment may require shifting strategies upon encountering new situations. Likewise, ...
    • Threat reversal learning and avoidance habits in generalised anxiety disorder. 

      Roberts, C; Apergis-Schoute, AM; Bruhl, A; Nowak, M; Baldwin, DS; Sahakian, BJ; Robbins, TW (2022-05-31)
      Avoidance and heightened responses to perceived threats are key features of anxiety disorders. These disorders are characterised by inflexibility in dynamically updating behavioural and physiological responses to aversively ...