Browsing School of Biological and Chemical Sciences by Author "Zanetti, G"
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Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation
Ilangovan, A; Kay, CWM; Roier, S; El Mkami, H; Salvadori, E; Zechner, EL; Zanetti, G; Waksman, G (Elsevier, 2017-05-04)Relaxases play essential roles in conjugation, the main process by which bacteria exchange genetic material, notably antibiotic resistance genes. They are bifunctional enzymes containing a trans-esterase activity, which ...