Browsing School of Biological and Chemical Sciences by Author "Quinn, DJ"
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Sequential Palladium-Catalyzed Allylic Alkylation/retro-Dieckmann Fragmentation Strategy for the Synthesis of α-Substituted Acrylonitriles.
Katsina, T; Sharma, SP; Buccafusca, R; Quinn, DJ; Moody, TS; Arseniyadis, S (2019-12-06)A straightforward synthesis of α-substituted acrylonitriles is described using 4-cyano-3-oxotetrahydro-thiophene (c-THT) as an acrylonitrile surrogate. This unprecedented two-step sequence featuring a palladium-catalyzed ...