dc.contributor.author | Balevicius, V | |
dc.contributor.author | Fox, K | |
dc.contributor.author | Bricker, WP | |
dc.contributor.author | Jurinovich, S | |
dc.contributor.author | Prandi, IG | |
dc.contributor.author | Mennucci, B | |
dc.contributor.author | DUFFY, CDP | |
dc.date.accessioned | 2017-10-31T11:27:11Z | |
dc.date.available | 2017-10-31T11:27:11Z | |
dc.date.issued | 2017-10 | |
dc.date.submitted | 2017-10-25T11:40:02.863Z | |
dc.identifier.citation | Balevičius, V., Fox, K., Bricker, W., Jurinovich, S., Prandi, I., Mennucci, B. and Duffy, C. (2017). Fine control of chlorophyll-carotenoid interactions defines the functionality of light-harvesting proteins in plants. [online] Scientific Reports. Available at: https://www.nature.com/articles/s41598-017-13720-6 [Accessed 31 Oct. 2017]. | en_US |
dc.identifier.issn | 2045-2322 | |
dc.identifier.other | 13956 | |
dc.identifier.other | 13956 | |
dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/28531 | |
dc.description.abstract | Photosynthetic antenna proteins can be thought of as “programmed solvents”, which bind pigments at specific mutual orientations, thus tuning the overall energetic landscape and ensuring highly efficient light-harvesting. While positioning of chlorophyll cofactors is well understood and rationalized by the principle of an “energy funnel”, the carotenoids still pose many open questions. Particularly, their short excited state lifetime (<25 ps) renders them potential energy sinks able to compete with the reaction centers and drastically undermine light-harvesting efficiency. Exploration of the orientational phase-space revealed that the placement of central carotenoids minimizes their interaction with the nearest chlorophylls in the plant antenna complexes LHCII, CP26, CP29 and LHCI. At the same time we show that this interaction is highly sensitive to structural perturbations, which has a profound effect on the overall lifetime of the complex. This links the protein dynamics to the light-harvesting regulation in plants by the carotenoids. | en_US |
dc.description.sponsorship | V.B. and C.D.P.D. acknowledge the support from the Leverhulme Trust RPG-2015-337. This research utilized Queen Mary’s MidPlus computational facilities, supported by QMUL Research-IT and funded by EPSRC grant EP/K000128/1. W.P.B acknowledges support from the Photosynthetic Antenna Research Center (PARC), an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award DE-SC0001035 for initial development of the TDC calculation code, as well as support from Army Research Office (ARO-MURI) Award W911NF1210420 for further development. | en_US |
dc.publisher | Nature Publishing Group | en_US |
dc.relation.ispartof | Scientific Reports | |
dc.relation.isreplacedby | 123456789/32292 | |
dc.relation.isreplacedby | http://qmro.qmul.ac.uk/xmlui/handle/123456789/32292 | |
dc.rights | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. | |
dc.subject | Computational biophysics | en_US |
dc.subject | Molecular dynamics | en_US |
dc.subject | Non-photochemical quenching | en_US |
dc.title | Fine control of chlorophyll-carotenoid interactions defines the functionality of light-harvesting proteins in plants | en_US |
dc.rights.holder | © The Author(s) 2017 | |
dc.identifier.doi | 10.1038/s41598-017-13720-6 | |
pubs.publication-status | Published | |
pubs.volume | 7 | |