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    Decision-making impairments in Parkinson's disease as a by-product of defective cost-benefit analysis and feedback processing. 
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    • School of Biological and Chemical Sciences
    • Decision-making impairments in Parkinson's disease as a by-product of defective cost-benefit analysis and feedback processing.
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    Decision-making impairments in Parkinson's disease as a by-product of defective cost-benefit analysis and feedback processing.

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    Submitted version (62.09Kb)
    Volume
    4
    Pagination
    317 - 327
    DOI
    10.2217/nmt.14.23
    Journal
    Neurodegener Dis Manag
    Issue
    4
    Metadata
    Show full item record
    Abstract
    Studies examining decision-making in people with Parkinson's disease (PD) show impaired performance on a variety of tasks. However, there are also demonstrations that patients with PD can make optimal decisions just like healthy age-matched controls. We propose that the reason for these mixed findings is that PD does not produce a generalized impairment of decision-making, but rather affects sub-components of this process. In this review we evaluate this hypothesis by considering the empirical evidence examining decision-making in PD. We suggest that of the various stages of the decision-making process, the most affected in PD are (1) the cost-benefit analysis stage and (2) the outcome evaluation stage. We consider the implications of this proposal for research in this area.
    Authors
    Ryterska, A; Jahanshahi, M; Osman, M
    URI
    http://qmro.qmul.ac.uk/xmlui/handle/123456789/10845
    Collections
    • School of Biological and Chemical Sciences [1925]
    Language
    eng
    Licence information
    CC-BY-NC.
    Copyright statements
    © 2016 Future Medicine
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