Browsing Library Administration by Subject "Saccharomyces cerevisiae"

Now showing items 1-3 of 3

    • Genome-wide screens in yeast models towards understanding chronological lifespan regulation. 

      Legon, L; Rallis, C (Oxford University Press, 2021-03-17)
      Cellular models such as yeasts are a driving force in biogerontology studies. Their simpler genome, short lifespans and vast genetic and genomics resources make them ideal to characterise pro-ageing and anti-ageing genes ...

    • Increased fidelity of protein synthesis extends lifespan. 

      Martinez-Miguel, VE; Lujan, C; Espie-Caullet, T; Martinez-Martinez, D; Moore, S; Backes, C; Gonzalez, S; Galimov, ER; Brown, AEX; Halic, M (Cell Press, 2021-09-14)
      Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the accuracy of translation, yet the physiological consequence of having fewer protein synthesis errors during multi-cellular organismal ...

    • Interplays of AMPK and TOR in Autophagy Regulation in Yeast. 

      Alao, J-P; Legon, L; Dabrowska, A; Tricolici, A-M; Kumar, J; Rallis, C (MDPI, 2023-02-04)
      Cells survey their environment and need to balance growth and anabolism with stress programmes and catabolism towards maximum cellular bioenergetics economy and survival. Nutrient-responsive pathways, such as the mechanistic ...