Now showing items 1-3 of 3

    • Genome-wide screens in yeast models towards understanding chronological lifespan regulation. 

      Legon, L; Rallis, C (Oxford University Press, 2021-03-17)
      Cellular models such as yeasts are a driving force in biogerontology studies. Their simpler genome, short lifespans and vast genetic and genomics resources make them ideal to characterise pro-ageing and anti-ageing genes ...
    • Increased fidelity of protein synthesis extends lifespan. 

      Martinez-Miguel, VE; Lujan, C; Espie-Caullet, T; Martinez-Martinez, D; Moore, S; Backes, C; Gonzalez, S; Galimov, ER; Brown, AEX; Halic, M (Cell Press, 2021-09-14)
      Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the accuracy of translation, yet the physiological consequence of having fewer protein synthesis errors during multi-cellular organismal ...
    • Nutrient-Response Pathways in Healthspan and Lifespan Regulation. 

      Dabrowska, A; Kumar, J; Rallis, C (MDPI, 2022-05-06)
      Cellular, small invertebrate and vertebrate models are a driving force in biogerontology studies. Using various models, such as yeasts, appropriate tissue culture cells, Drosophila, the nematode Caenorhabditis elegans and ...