Browsing Library Administration by Author "Sutton, BJ"

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    • Crystal structures of the human IgD Fab reveal insights into CH1 domain diversity 

      Davies, AM; Beavil, RL; Barbolov, M; Sandhar, BS; Gould, HJ; Beavil, AJ; Sutton, BJ; McDonnell, JM (Elsevier, 2023-06-01)
      Antibodies of the IgD isotype remain the least well characterized of the mammalian immunoglobulin isotypes. Here we report three-dimensional structures for the Fab region of IgD, based on four different crystal structures, ...

    • Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor. 

      Vester, SK; Davies, AM; Beavil, RL; Sandhar, BS; Beavil, AJ; Gould, HJ; Sutton, BJ; McDonnell, JM (MDPI, 2023-11-16)
      We have previously produced a toolkit of antibodies, comprising recombinant human antibodies of all but one of the human isotypes, directed against the polcalcin family antigen Phl p 7. In this work, we complete the toolkit ...