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    AuthorManchanda, R (25)Mathur, R (17)Priebe, S (14)Baumbach, A (13)Lawn, JE (12)Menon, U (12)Day, LT (11)Korbonits, M (11)Mathur, A (11)Petersen, SE (11)... View MoreSubject
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    Humans (659)Male (510)Adult (320)Middle Aged (311)Aged (238)Young Adult (138)Adolescent (132)Aged, 80 and over (81)Child (80)... View MoreDate Issued2020 - 2023 (120)2010 - 2019 (546)2000 - 2009 (12)1990 - 1999 (11)
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    TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. 

    Ottaviani, S; Stebbing, J; Frampton, AE; Zagorac, S; Krell, J; de Giorgio, A; Trabulo, SM; Nguyen, VTM; Magnani, L; Feng, H;... (2018-05-10)
    TGF-β/Activin induces epithelial-to-mesenchymal transition and stemness in pancreatic ductal adenocarcinoma (PDAC). However, the microRNAs (miRNAs) regulated during this response have remained yet undetermined. Here, we ...
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    A risk prediction algorithm for ovarian cancer incorporating BRCA1, BRCA2, common alleles and other familial effects. 

    Jervis, S; Song, H; Lee, A; Dicks, E; Harrington, P; Baynes, C; Manchanda, R; Easton, DF; Jacobs, I; Pharoah, PPD;... (2015-07)
    BACKGROUND: Although BRCA1 and BRCA2 mutations account for only ∼27% of the familial aggregation of ovarian cancer (OvC), no OvC risk prediction model currently exists that considers the effects of BRCA1, BRCA2 and other ...
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    Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors. 

    Saunderson, EA; Stepper, P; Gomm, JJ; Hoa, L; Morgan, A; Allen, MD; Jones, JL; Gribben, JG; Jurkowski, TP; Ficz, G (2017-11-13)
    Aberrant promoter DNA hypermethylation is a hallmark of cancer; however, whether this is sufficient to drive cellular transformation is not clear. To investigate this question, we use a CRISPR-dCas9 epigenetic editing tool, ...
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    Barriers to HPV self-sampling and cytology among low-income indigenous women in rural areas of a middle-income setting: a qualitative study. 

    Allen-Leigh, B; Uribe-Zúñiga, P; León-Maldonado, L; Brown, BJ; Lörincz, A; Salmeron, J; Lazcano-Ponce, E (2017-11-09)
    BACKGROUND: Data is needed about barriers to self-collection of Human Papillomavirus (HPV) samples and cytology among low-income, disadvantaged women living in rural areas of lower-income countries as these women are at ...
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    Prospective association between handgrip strength and cardiac structure and function in UK adults. 

    Beyer, SE; Sanghvi, MM; Aung, N; Hosking, A; Cooper, JA; Paiva, JM; Lee, AM; Fung, K; Lukaschuk, E; Carapella, V;... (2018)
    BACKGROUND: Handgrip strength, a measure of muscular fitness, is associated with cardiovascular (CV) events and CV mortality but its association with cardiac structure and function is unknown. The goal of this study was ...
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    Human papilloma virus genotyping for the cross-sectional and longitudinal probability of developing cervical intraepithelial neoplasia grade 2 or more. 

    Del Mistro, A; Adcock, R; Carozzi, F; Gillio-Tos, A; De Marco, L; Girlando, S; Rizzolo, R; Frayle, H; Trevisan, M; Sani, C;... (2018-07-15)
    Human papilloma virus (HPV) testing is more sensitive but less specific than cytology. We evaluated stand-alone genotyping as a possible triage method. During a multicentre randomised controlled trial comparing HPV testing ...
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    New strategies for human papillomavirus-based cervical screening. 

    Lorincz, A; Castanon, A; Wey Lim, AW; Sasieni, P (2013-09)
    Human papillomavirus testing has been shown to be far more sensitive and robust in detecting cervical intraepithelial neoplasia 2 and above (and cervical intraepithelial neoplasia 3 and above) for cervical screening than ...
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    Cone depth increases risk of adverse obstetric outcomes following treatment for cervical preinvasive disease. 

    Castanon, A (2017-03)
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    Neither phylogenomic nor palaeontological data support a Palaeogene origin of placental mammals. 

    dos Reis, M; Donoghue, PCJ; Yang, Z (2014-01)
    O'Leary et al. (O'Leary et al. 2013 Science 339, 662-667. (doi:10.1126/science.1229237)) performed a fossil-only dating analysis of mammals, concluding that the ancestor of placentals post-dated the Cretaceous-Palaeogene ...
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    Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. 

    Ramírez, J; Duijvenboden, SV; Ntalla, I; Mifsud, B; Warren, HR; Tzanis, E; Orini, M; Tinker, A; Lambiase, PD; Munroe, PB (2018-05-16)
    Impaired capacity to increase heart rate (HR) during exercise (ΔHRex), and a reduced rate of recovery post-exercise (ΔHRrec) are associated with higher cardiovascular mortality rates. Currently, the genetic basis of both ...
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