Search
Now showing items 131-140 of 147
Safety and efficacy of duodenal stent insertion for gastric outlet obstruction: characterisation of a regional district general hospital service.
(2020-11)
INTRODUCTION: Placement of a duodenal or pyloric stent is a recognised palliative procedure for symptomatic relief of malignant gastric outlet obstruction. This procedure can be associated with significant complications, ...
The Changing Face of Emergency General Surgery: A 20-year Analysis of Secular Trends in Demographics, Diagnoses, Operations, and Outcomes.
(2020-03)
OBJECTIVE: The aim of the study was to evaluate secular trends in the epidemiology of emergency general surgery (EGS), by analyzing changes in demographics, diagnoses, operations, and outcomes between 1997 and 2016. SUMMARY ...
Twenty-year study of in-hospital and postdischarge mortality following emergency general surgical admission.
(2019-10)
BACKGROUND: Emergency general surgery (EGS) patients have a higher mortality than those having elective surgery. Few studies have investigated changes in EGS-associated mortality over time or explored mortality rates after ...
Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3.
(2021-05)
Platelet activation and pulmonary recruitment occur in patients with asthma and in animal models of allergic asthma, in which leukocyte infiltration, airway remodeling, and hyperresponsiveness are suppressed by experimental ...
Use of repurposed and adjuvant drugs in hospital patients with covid-19: multinational network cohort study.
(2021-05-11)
OBJECTIVE: To investigate the use of repurposed and adjuvant drugs in patients admitted to hospital with covid-19 across three continents. DESIGN: Multinational network cohort study. SETTING: Hospital electronic health ...
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
(2021-03)
Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry, and their expression may shed light on viral ...
UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia.
(2014-02-06)
The Philadelphia chromosome positive arm of the UKALLXII/ECOG2993 study for adult acute lymphoblastic leukemia (ALL) enrolled 266 patients between 1993 and 2003 (pre-imatinib cohort). In 2003 imatinib was introduced as a ...
20 Risk factors for admission at three, urban emergency departments in england: a cross-sectional analysis of attendances over one month.
(2017-12)
OBJECTIVE: To investigate factors associated with unscheduled admission following presentation to Emergency Departments (EDs) at three hospitals in England. DESIGN AND SETTING: Cross-sectional analysis of attendance data ...
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic.
(2013-12-12)
The GGGGCC (G4C2) intronic repeat expansion within C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Intranuclear neuronal RNA foci have been observed in ALS ...