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Now showing items 41-50 of 188
Monetary cost for time spent in everyday physical activities.
(2014-05)
We measured utility curves for the hypothetical monetary costs as a function of time engaged in three everyday physical activities: walking, standing, and sitting. We found that activities requiring more physical exertion ...
Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial.
(2017-11-18)
BACKGROUND: Guidelines for hypertension vary in their preference for initial combination therapy or initial monotherapy, stratified by patient profile; therefore, we compared the efficacy and tolerability of these approaches. ...
Association of genetic variation in telomere-related SNP and telomerase with ventricular arrhythmias in ischemic cardiomyopathy.
(2018-03)
BACKGROUND: Telomeres are known to provide genomic stability and telomere length has been associated with cardiovascular diseases. Moreover, a higher telomerase activity has been shown to be associated with ventricular ...
Carbonaceous particulate matter on the lung surface from adults living in São Paulo, Brazil.
(2017)
OBJECTIVES: We therefore sought to identify the exposures associated with lung surface in long-term residents of São Paulo, Brazil. METHODS: Lung surface carbon were analyzed in 72 autopsy specimens by image analysis. ...
Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial.
(Elsevier/Science Direct, 2018-04-10)
BACKGROUND: In sub-Saharan Africa, severely immunocompromised HIV-infected individuals have a high risk of mortality during the first few months after starting antiretroviral therapy (ART). We hypothesise that universally ...
Elbasvir/grazoprevir and sofosbuvir for hepatitis C virus genotype 3 infection with compensated cirrhosis: A randomized trial.
(2018-06)
Many direct-acting antiviral regimens have reduced activity in people with hepatitis C virus (HCV) genotype (GT) 3 infection and cirrhosis. The C-ISLE study assessed the efficacy and safety of elbasvir/grazoprevir (EBR/GZR) ...
Interpreting population reach of a large, successful physical activity trial delivered through primary care.
(BioMed Central Ltd, 2018-01-23)
BACKGROUND: Failure to include socio-economically deprived or ethnic minority groups in physical activity (PA) trials may limit representativeness and could lead to implementation of interventions that then increase health ...
Cross Sectional Associations between Socio-Demographic Factors and Cognitive Performance in an Older British Population: The European Investigation of Cancer in Norfolk (EPIC-Norfolk) Study.
(2016)
BACKGROUND: Cognition covers a range of abilities, such as memory, response time and language, with tests assessing either specific or generic aspects. However differences between measures may be observed within the same ...
Welfare states, the Great Recession and health: Trends in educational inequalities in self-reported health in 26 European countries.
(2018)
BACKGROUND: Although socioeconomic inequalities in health have long been observed in Europe, few studies have analysed their recent patterning. In this paper, we examined how educational inequalities in self-reported health ...
Ethnic differences in the progression of chronic kidney disease and risk of death in a UK diabetic population: an observational cohort study.
(2018-03-27)
OBJECTIVE: To determine ethnic differences in the progression of chronic kidney disease (CKD) and risk of end-stage renal failure (ESRF) and death in adults with type 2 diabetes mellitus (T2DM), and to identify predictors ...